Electrochemical Determination of Uric Acid in Urine by Using Zeolite Imidazolate Framework-11 Modified Electrode

In the present article, synthesis of zeolite imidazole framework-11 (ZIF-11) by ultrasonic-assisted hydrothermal process and its application as an electrode modifier for electrochemical determination uric acid in urine are demonstrated. The obtained materials were characterized X-ray diffraction (XRD), scanning electron microscopy (SEM), nitrogen adsorption/desorption isotherms. It was found that ZIF-11 with rhombic dodecahedron topology high surface area (1066 m2.g-1) synthesized a certain temperature around 25–40°C, other crystalline phases zinc benzimidazolate deferring from phase less 25°C or higher than 40°C. is stable pH range 6-10. modification glassy carbon performed ZIF-67 using drop-casting procedure. modified employed to study behavior (UA). UA oxidation catalyzed this aqueous buffer solution (pH 7) decrease 70 mV overpotential compared electrode. With differential pulse–anodic stripping voltammetry (DP-ASV) method, current versus concentration shows good linearity 20–540?M ( R = 0.998 ) detection limit 0.48 ?M id="M2"> S / N 3 ). applied content samples, satisfied results obtained.